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Upstream Bio Inc

UPB

NASDAQ

Biotechnology

$7.07

USD

+0.16 (+2.32%)

At close: Aug 14, 2026, 4:00 PM EDT

Market Cap $397.81M

Volume 688.2K

Revenue

$3.16M

TTM

YoY

Gross Margin

100%

TTM

YoY

Net Income

$-156.50M

TTM

YoY

Operating Cash Flow

$-136.34M

TTM

YoY

Revenue & Net Income

USD Millions

Margins Trend

Percent of revenue

Income Statement Detail

USD Millions, except per-share and share count figures

Metric

Q2 2025

Q3 2025

Q4 2025

Q1 2026

Q2 2026

Revenue

0.9

0.7

0.7

1.0

0.8

YoY Growth

+9.0%

+82.7%

-17.5%

Cost of Revenue

0.0

0.0

0.0

0.0

0.0

Gross Profit

0.9

0.7

0.7

1.0

0.8

Selling, General & Administrative

7.4

5.5

6.7

8.1

7.1

Other Operating Expenses

0.0

0.0

0.0

0.0

0.0

Total Operating Expenses

45.3

38.5

46.8

44.6

43.1

Operating Income

-44.3

-37.8

-46.2

-43.6

-42.4

EBITDA

-44.3

-37.8

-46.1

-43.6

-42.3

Other Income / Expense

-0.1

-0.0

0.1

-0.0

0.0

Total Other Income / Expense

4.4

4.1

3.7

3.0

2.7

Income Before Income Taxes

-40.0

-33.7

-42.5

-40.6

-39.7

Income Taxes

0.0

0.0

0.0

0.0

0.0

Net Income

-40.0

-33.7

-42.5

-40.6

-39.7

Consolidated Net Income / Loss

-40.0

-33.7

-42.5

-40.6

-39.7

Net Income Attributable to Common Shareholders

-40.0

-33.7

-42.5

-40.6

-39.7

Basic EPS

-$0.74

-$0.63

-$0.78

-$0.75

-$0.73

Diluted EPS

-$0.74

-$0.63

-$0.78

-$0.75

-$0.73

Basic Shares Outstanding

53.8M

53.9M

54.1M

54.3M

54.6M

Diluted Shares Outstanding

53.8M

53.9M

54.1M

54.3M

54.6M