Twist Bioscience Corp
TWST
NASDAQ
Biotechnology
$118.57
USD
-6.72 (-5.36%)
At close: Aug 14, 2026, 4:00 PM EDT
Market Cap $8.23B
Volume 1.1M
About Twist Bioscience Corp
Twist Bioscience Corp. engages in the development of a proprietary semiconductor-based synthetic DNA manufacturing process. The company is headquartered in South San Francisco, California and currently employs 979 full-time employees. The company went IPO on 2018-10-31. The firm's proprietary silicon-based platform delivers precision, scale, and speed, supporting consistent, high-quality performance across a range of applications. The Company’s platform is a differentiated method of manufacturing synthetic deoxyribonucleic acid (DNA) by writing DNA on a silicon chip. By integrating proprietary hardware, software, and scalable infrastructure, including its e-commerce platform. The firm has extended this platform beyond DNA synthesis to offer an integrated portfolio that includes synthetic genes, next-generation sequencing, applications, sample preparation tools, antibody libraries, and biologic discovery services. Leveraging the same platform, it also manufactures synthetic ribonucleic acid (RNA) and expresses antibody proteins.
CEO
Dr. Emily Leproust
HQ
South San Francisco, CALIFORNIA, US
Founded
2018
Employees
979
Quantli Score
8.4
Outperform
Fin. Health
8.1
Profitability
7.6
Growth
9.0
Cash-Flow Q.
8.8
Key Metrics
6 metrics our research team weighs before forming a view on TWST.
Based on Quantli research · SEC filings · as of Q2 2026
METRIC
VALUE
CHANGE
TREND (3Y)
Revenue Growth (TTM)
17.8%
-7.5 pp
Gross Margin (TTM)
52.1%
+5.4 pp
Operating Margin (TTM)
-33.9%
+24.0 pp
Net Margin (TTM)
-19.8%
+35.1 pp
ROE (TTM)
-17.9%
+25.6 pp
Free Cash Flow (TTM)
$-100.04M
—
Financial Snapshot
Revenue
$409.48M
+17.8%
YoY
Gross Margin
52%
TTM
+11.5%
YoY
Net Income
$-81.28M
+57.5%
YoY
Operating Cash Flow
$-55.59M
+0.9%
YoY
Key Statistics
Open
$124.09
Previous Close
$125.29
Day Range
$118.44 - $124.71
52 Week Range
$23.30 - $126.40
Volume
1.1M
Average Volume (10 Days)
1.9M
Dividend Yield
—
Valuation Measurement
Market Cap
$8.23B
P/E Ratio (TTM)
—
P/S Ratio (TTM)
20.11
Price / Book
18.09
Financial Highlights
Profit Margin
-19.8%
Return on Assets
-12.0%
Return on Equity
-17.9%
Revenue (TTM)
$409.48M
Net Income (TTM)
$-81.28M
Diluted EPS (TTM)
-$1.34
Total Cash (MRQ)
$122.67M
Levered FCF (TTM)
$-100.04M
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Earnings Calendar
Next Earnings
Estimated Q4 Release
Nov 12
Est. EPS
Adjusted consensus estimate
-$0.40
Analyst Consensus
Based on 7 analyst ratings
Avg Target: $101.86
(-14.1% upside)
High: $120.00 · Low: $85.00
Strong Buy
0%
Buy
86%
Hold
14%
Sell
0%
Strong Sell
0%