Rhythm Pharmaceuticals Inc
RYTM
NASDAQ
Biotechnology
$115.48
USD
-0.54 (-0.47%)
At close: Aug 14, 2026, 4:00 PM EDT
Market Cap $8.14B
Volume 334.9K
About Rhythm Pharmaceuticals Inc
Rhythm Pharmaceuticals, Inc. is a commercial-stage biopharmaceutical company, which engages in the development and commercialization of therapeutics for patients with rare diseases. The company is headquartered in Boston, Massachusetts and currently employs 414 full-time employees. The company went IPO on 2017-10-05. The firm's lead asset, IMCIVREE, is an MC4R agonist designed to treat hyperphagia and severe obesity, is approved by the Food and Drug Administration (FDA) to reduce excess body weight and maintain reduction long term in adults and pediatric patients aged four years and older with acquired hypothalamic obesity, adult and pediatric patients two years of age and older with syndromic or monogenic obesity due to Bardet-Biedl syndrome (BBS) or genetically confirmed pro-opiomelanocortin (POMC), including proprotein convertase subtilisin/kexin type 1 (PCSK1), deficiency or leptin receptor (LEPR) deficiency. In addition to it the Company is advancing a broad clinical development program for setmelanotide in other rare diseases, as well as investigational MC4R agonists bivamelagon and RM-718, and a preclinical suite of small molecules for the treatment of congenital hyperinsulinism.
CEO
Dr. David Meeker
HQ
Boston, MASSACHUSETTS, US
Founded
2017
Employees
414
Quantli Score
8.4
Outperform
Fin. Health
8.1
Profitability
7.6
Growth
9.0
Cash-Flow Q.
8.8
Key Metrics
6 metrics our research team weighs before forming a view on RYTM.
Based on Quantli research · SEC filings · as of Q2 2026
METRIC
VALUE
CHANGE
TREND (3Y)
Revenue Growth (TTM)
53.5%
-0.0 pp
Gross Margin (TTM)
89.0%
-0.2 pp
Operating Margin (TTM)
-83.6%
+29.9 pp
Net Margin (TTM)
-85.6%
+31.6 pp
ROE (TTM)
-199.4%
—
Free Cash Flow (TTM)
$-106.30M
—
Financial Snapshot
Revenue
$239.92M
+53.5%
YoY
Gross Margin
89%
TTM
-0.3%
YoY
Net Income
$-205.35M
-12.2%
YoY
Operating Cash Flow
$-105.35M
+2.2%
YoY
Key Statistics
Open
$115.22
Previous Close
$116.02
Day Range
$113.66 - $117.33
52 Week Range
$74.50 - $122.20
Volume
334.9K
Average Volume (10 Days)
860.0K
Dividend Yield
—
Valuation Measurement
Market Cap
$8.14B
P/E Ratio (TTM)
—
P/S Ratio (TTM)
33.92
Price / Book
79.01
Financial Highlights
Profit Margin
-85.6%
Return on Assets
-47.0%
Return on Equity
-199.4%
Revenue (TTM)
$239.92M
Net Income (TTM)
$-205.35M
Diluted EPS (TTM)
-$3.11
Total Cash (MRQ)
$65.61M
Levered FCF (TTM)
$-106.30M
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Earnings Calendar
Next Earnings
Estimated Q3 Release
Nov 02
Est. EPS
Adjusted consensus estimate
-$0.78
Analyst Consensus
Based on 3 analyst ratings
Avg Target: $150.33
(+30.2% upside)
High: $155.00 · Low: $145.00
Strong Buy
0%
Buy
100%
Hold
0%
Sell
0%
Strong Sell
0%