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Crescent Biopharma Inc

CBIO

NASDAQ

Biotechnology

$17.14

USD

+0.51 (+3.07%)

At close: Aug 14, 2026, 4:00 PM EDT

Market Cap $617.70M

Volume 229.9K

Price (USD)
Price (USD)

About Crescent Biopharma Inc

Crescent Biopharma, Inc. operates as a biopharmaceutical company that develops and designs small molecule therapeutics to treat cancers. The company is headquartered in Waltham, Massachusetts and currently employs 44 full-time employees. The company went IPO on 2014-01-10. The firm is focused on advancing the next wave of therapies for cancer patients. The Company’s pipeline includes its lead program, a PD-1 x VEGF bispecific antibody, as well as novel antibody-drug conjugates. The Company’s lead program is CR-001, a tetravalent PD-1 x VEGF bispecific antibody in development for the treatment of solid tumors, and it is also advancing CR-002 and CR-003, antibody drug conjugates (ADCs) with topoisomerase inhibitor payloads. CR-002 and CR-003 are ADCs designed to deliver clinically active cytotoxic drugs known as topoisomerase inhibitors to tumor cells. Each of these programs has the potential to deliver therapeutics with clinical efficacy both as a monotherapy and in combination with CR-001 with significant potential across solid tumor indications.

CEO

Mr. Bruce Johnson

HQ

Waltham, MASSACHUSETTS, US

Founded

2014

Employees

55

Quantli Score

8.4

Outperform

Fin. Health

8.1

Profitability

7.6

Growth

9.0

Cash-Flow Q.

8.8

Key Metrics

6 metrics our research team weighs before forming a view on CBIO.

Based on Quantli research · SEC filings · as of Q2 2026

METRIC

VALUE

CHANGE

TREND (3Y)

Revenue Growth (TTM)

-86.2%

-70.6 pp

Gross Margin (TTM)

100.0%

+3.9 pp

Operating Margin (TTM)

-1417.7%

-1421.6 pp

Net Margin (TTM)

-1389.6%

-1382.3 pp

ROE (TTM)

-101.1%

-96.6 pp

Free Cash Flow (TTM)

$-73.62M

Financial Snapshot

Full Financials

Revenue

$11.88M

-86.2%

YoY

Gross Margin

100%

TTM

+4.1%

YoY

Net Income

$-165.12M

-2523.9%

YoY

Operating Cash Flow

$-72.68M

-1285.6%

YoY

Key Statistics

Open

$16.61

Previous Close

$16.63

Day Range

$16.05 - $17.36

52 Week Range

$8.72 - $27.41

Volume

229.9K

Average Volume (10 Days)

200.0K

Dividend Yield

Valuation Measurement

Market Cap

$617.70M

P/E Ratio (TTM)

P/S Ratio (TTM)

51.98

Price / Book

3.78

Financial Highlights

Profit Margin

-1389.6%

Return on Assets

-90.4%

Return on Equity

-101.1%

Revenue (TTM)

$11.88M

Net Income (TTM)

$-165.12M

Diluted EPS (TTM)

-$6.67

Total Cash (MRQ)

$171.59M

Levered FCF (TTM)

$-73.62M

Turn research into action

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Swing Strategy

Buy support, sell on recovery.

Best for:

Risk-tolerant

Trend Following

Enter on trend. Cut losses fast.

Best for:

Active traders

Position Strategy

Ride market cycles. Patient hold.

Best for:

Patient investors

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Earnings Calendar

Next Earnings

Estimated Q3 Release

Nov 04

Est. EPS

Adjusted consensus estimate

-$0.79