Crescent Biopharma Inc
CBIO
NASDAQ
Biotechnology
$17.14
USD
+0.51 (+3.07%)
At close: Aug 14, 2026, 4:00 PM EDT
Market Cap $617.70M
Volume 229.9K
About Crescent Biopharma Inc
Crescent Biopharma, Inc. operates as a biopharmaceutical company that develops and designs small molecule therapeutics to treat cancers. The company is headquartered in Waltham, Massachusetts and currently employs 44 full-time employees. The company went IPO on 2014-01-10. The firm is focused on advancing the next wave of therapies for cancer patients. The Company’s pipeline includes its lead program, a PD-1 x VEGF bispecific antibody, as well as novel antibody-drug conjugates. The Company’s lead program is CR-001, a tetravalent PD-1 x VEGF bispecific antibody in development for the treatment of solid tumors, and it is also advancing CR-002 and CR-003, antibody drug conjugates (ADCs) with topoisomerase inhibitor payloads. CR-002 and CR-003 are ADCs designed to deliver clinically active cytotoxic drugs known as topoisomerase inhibitors to tumor cells. Each of these programs has the potential to deliver therapeutics with clinical efficacy both as a monotherapy and in combination with CR-001 with significant potential across solid tumor indications.
CEO
Mr. Bruce Johnson
HQ
Waltham, MASSACHUSETTS, US
Founded
2014
Employees
55
Quantli Score
8.4
Outperform
Fin. Health
8.1
Profitability
7.6
Growth
9.0
Cash-Flow Q.
8.8
Key Metrics
6 metrics our research team weighs before forming a view on CBIO.
Based on Quantli research · SEC filings · as of Q2 2026
METRIC
VALUE
CHANGE
TREND (3Y)
Revenue Growth (TTM)
-86.2%
-70.6 pp
Gross Margin (TTM)
100.0%
+3.9 pp
Operating Margin (TTM)
-1417.7%
-1421.6 pp
Net Margin (TTM)
-1389.6%
-1382.3 pp
ROE (TTM)
-101.1%
-96.6 pp
Free Cash Flow (TTM)
$-73.62M
—
Financial Snapshot
Revenue
$11.88M
-86.2%
YoY
Gross Margin
100%
TTM
+4.1%
YoY
Net Income
$-165.12M
-2523.9%
YoY
Operating Cash Flow
$-72.68M
-1285.6%
YoY
Key Statistics
Open
$16.61
Previous Close
$16.63
Day Range
$16.05 - $17.36
52 Week Range
$8.72 - $27.41
Volume
229.9K
Average Volume (10 Days)
200.0K
Dividend Yield
—
Valuation Measurement
Market Cap
$617.70M
P/E Ratio (TTM)
—
P/S Ratio (TTM)
51.98
Price / Book
3.78
Financial Highlights
Profit Margin
-1389.6%
Return on Assets
-90.4%
Return on Equity
-101.1%
Revenue (TTM)
$11.88M
Net Income (TTM)
$-165.12M
Diluted EPS (TTM)
-$6.67
Total Cash (MRQ)
$171.59M
Levered FCF (TTM)
$-73.62M
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Earnings Calendar
Next Earnings
Estimated Q3 Release
Nov 04
Est. EPS
Adjusted consensus estimate
-$0.79