Spero Therapeutics Inc
SPRO
NASDAQ
Biotechnology
$1.23
USD
-0.01 (-0.81%)
At close: Aug 14, 2026, 4:00 PM EDT
Market Cap $72.09M
Volume 744.5K
About Spero Therapeutics Inc
Spero Therapeutics, Inc. is a clinical-stage biopharmaceutical company, which focuses on identifying, developing, and commercializing treatments involving bacterial infections, including multi-drug resistant bacterial infections, and rare diseases Its pipeline product candidates include Tebipenem HBr, SPR720, and SPR206. The company is headquartered in Cambridge, Massachusetts and currently employs 25 full-time employees. The company went IPO on 2017-11-02. The firm is focused on identifying and developing novel treatments for rare diseases and diseases caused by multi-drug resistant (MDR) bacterial infections with unmet need. Its product candidate SPR720 is an investigational, chemically stable phosphate ester prodrug that is converted in vivo to SPR719 for the treatment of nontuberculous mycobacterial (NTM) pulmonary disease. Its clinical stage product candidate, tebipenem HBr is an investigational oral carbapenem antibiotic being developed for the treatment of complicated urinary tract infections (cUTIs) including acute pyelonephritis (AP) to help patients potentially reduce duration of in-patient therapy.
CEO
Ms. Esther Rajavelu
HQ
Cambridge, MASSACHUSETTS, US
Founded
2017
Employees
25
Quantli Score
8.4
Outperform
Fin. Health
8.1
Profitability
7.6
Growth
9.0
Cash-Flow Q.
8.8
Key Metrics
6 metrics our research team weighs before forming a view on SPRO.
Based on Quantli research · SEC filings · as of Q1 2026
METRIC
VALUE
CHANGE
TREND (3Y)
Revenue Growth (TTM)
37.2%
+97.1 pp
Gross Margin (TTM)
100.0%
0.0 pp
Operating Margin (TTM)
22.1%
+188.3 pp
Net Margin (TTM)
24.9%
+181.4 pp
ROE (TTM)
28.8%
+235.1 pp
Free Cash Flow (TTM)
$7.24M
—
Financial Snapshot
Revenue
$61.19M
+37.2%
YoY
Gross Margin
100%
TTM
0.0%
YoY
Net Income
$15.23M
+121.8%
YoY
Operating Cash Flow
$7.24M
+121.7%
YoY
Key Statistics
Open
$1.26
Previous Close
$1.24
Day Range
$1.19 - $1.26
52 Week Range
$1.08 - $3.08
Volume
744.5K
Average Volume (10 Days)
770.0K
Dividend Yield
—
Valuation Measurement
Market Cap
$72.09M
P/E Ratio (TTM)
4.73
P/S Ratio (TTM)
1.18
Price / Book
1.36
Financial Highlights
Profit Margin
24.9%
Return on Assets
25.8%
Return on Equity
28.8%
Revenue (TTM)
$61.19M
Net Income (TTM)
$15.23M
Diluted EPS (TTM)
$0.17
Total Cash (MRQ)
$56.13M
Levered FCF (TTM)
$7.24M
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Earnings Calendar
Next Earnings
Estimated Q3 Release
Nov 11
Est. EPS
Adjusted consensus estimate
-$0.16