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Prime Medicine Inc

PRME

NASDAQ

Biotechnology

$3.09

USD

-0.08 (-2.52%)

At close: Aug 14, 2026, 4:00 PM EDT

Market Cap $574.96M

Volume 1.6M

Price (USD)
Price (USD)

About Prime Medicine Inc

Prime Medicine, Inc. is a biotechnology company, which engages in developing one-time curative genetic therapies. The company is headquartered in Cambridge, Massachusetts and currently employs 146 full-time employees. The company went IPO on 2022-10-20. The company deploys its proprietary Prime Editing platform, a versatile, precise and efficient gene editing technology, to develop a new class of differentiated one-time curative genetic therapies. The company is advancing a set of high-value programs across its core areas of focus (hematology, immunology and oncology, liver, and lung). These include ex vivo hematopoietic stem cell (HSC) programs for the treatment of p47phox chronic granulomatous disease CGD and X-linked CGD; a lipid nanoparticle (LNP) Prime Editor for the treatment of Wilson’s Disease; a LNP or adeno-associated virus Prime Editors for the treatment of cystic fibrosis; and ex vivo T-cell therapies. PM359, its product candidate within its hematology, immunology and oncology area of focus, targets the p47phox variant of CGD. Its PM577 comprises a Prime Editor encapsulated as RNA cargo in a liver-targeted LNP.

CEO

Dr. Allan Reine

HQ

Cambridge, MASSACHUSETTS, US

Founded

2022

Employees

146

Quantli Score

8.4

Outperform

Fin. Health

8.1

Profitability

7.6

Growth

9.0

Cash-Flow Q.

8.8

Key Metrics

6 metrics our research team weighs before forming a view on PRME.

Based on Quantli research · SEC filings · as of Q2 2026

METRIC

VALUE

CHANGE

TREND (3Y)

Revenue Growth (TTM)

-17.9%

-757.3 pp

Gross Margin (TTM)

100.0%

0.0 pp

Operating Margin (TTM)

-4824.9%

-708.4 pp

Net Margin (TTM)

-4613.1%

-596.3 pp

ROE (TTM)

-472.0%

-144.6 pp

Free Cash Flow (TTM)

$-156.85M

Financial Snapshot

Full Financials

Revenue

$4.07M

-17.9%

YoY

Gross Margin

100%

TTM

0.0%

YoY

Net Income

$-187.89M

+5.7%

YoY

Operating Cash Flow

$-156.05M

-56.2%

YoY

Key Statistics

Open

$3.14

Previous Close

$3.17

Day Range

$3.00 - $3.14

52 Week Range

$2.67 - $6.94

Volume

1.6M

Average Volume (10 Days)

2.6M

Dividend Yield

Valuation Measurement

Market Cap

$574.96M

P/E Ratio (TTM)

P/S Ratio (TTM)

141.16

Price / Book

14.44

Financial Highlights

Profit Margin

-4613.1%

Return on Assets

-75.4%

Return on Equity

-472.0%

Revenue (TTM)

$4.07M

Net Income (TTM)

$-187.89M

Diluted EPS (TTM)

-$1.10

Total Cash (MRQ)

$47.45M

Levered FCF (TTM)

$-156.85M

Turn research into action

Knowing a stock is strong is the start. Knowing how to invest in it when you spot good research is good returns.

Swing Strategy

Buy support, sell on recovery.

Best for:

Risk-tolerant

Position Strategy

Ride market cycles. Patient hold.

Best for:

Patient investors

Trend Following

Enter on trend. Cut losses fast.

Best for:

Active traders

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Earnings Calendar

Next Earnings

Estimated Q3 Release

Nov 05

Est. EPS

Adjusted consensus estimate

-$0.25

Analyst Consensus

Buy

Based on 1 analyst ratings

Avg Target: $8.00

(+158.9% upside)

High: $8.00 · Low: $8.00

Strong Buy

0%

Buy

100%

Hold

0%

Sell

0%

Strong Sell

0%

View full analyst ratings