Ensysce Biosciences Inc
ENSC
NASDAQ
Biotechnology
$0.40
USD
+0.05 (+14.75%)
At close: Aug 14, 2026, 4:00 PM EDT
Market Cap $5.23M
Volume 18.2M
About Ensysce Biosciences Inc
Ensysce Biosciences, Inc. is a clinical-stage biopharmaceutical company, which engages in the development of solutions for severe pain relief while reducing the fear of and the potential for misuse and overdose. The company is headquartered in La Jolla, California and currently employs 8 full-time employees. The company went IPO on 2017-12-01. The firm develops solutions for severe pain relief while reducing the potential for opioid misuse, abuse, and overdose. Its pipeline includes two new drug platforms: an abuse-resistant opioid prodrug technology, the Trypsin Activated Abuse Protection (TAAP) platform, and an over-dose protection opioid prodrug technology, the Multi-Pill Abuse Resistant (MPAR) platform. Its lead product, PF614, is a TAAP extended-release oxycodone and a potential analgesic to treat severe pain. Its second product, PF614-MPAR, is to treat severe pain with the added benefit of oral overdose protection, is a combination product of the TAAP prodrug PF614 with a trypsin inhibitor. Additionally, nafamostat, which is an ingredient in its overdose protection combination products, is also being developed for the intended purpose of treating infection and pulmonary lung diseases.
CEO
Dr. Lynn Kirkpatrick
HQ
La Jolla, CALIFORNIA, US
Founded
2017
Employees
8
Quantli Score
8.4
Outperform
Fin. Health
8.1
Profitability
7.6
Growth
9.0
Cash-Flow Q.
8.8
Key Metrics
5 metrics our research team weighs before forming a view on ENSC.
Based on Quantli research · SEC filings · as of Q1 2026
METRIC
VALUE
CHANGE
TREND (3Y)
Revenue Growth (TTM)
-24.4%
-280.7 pp
Gross Margin (TTM)
100.0%
0.0 pp
Operating Margin (TTM)
-251.4%
-141.3 pp
Net Margin (TTM)
-250.4%
-140.9 pp
Free Cash Flow (TTM)
$-9.72M
—
Financial Snapshot
Revenue
$4.71M
-24.4%
YoY
Gross Margin
100%
TTM
0.0%
YoY
Net Income
$-11.79M
-72.9%
YoY
Operating Cash Flow
$-9.60M
-65.5%
YoY
Key Statistics
Open
$0.34
Previous Close
$0.35
Day Range
$0.33 - $0.47
52 Week Range
$0.23 - $2.75
Volume
18.2M
Average Volume (10 Days)
83.7M
Dividend Yield
—
Valuation Measurement
Market Cap
$5.23M
P/E Ratio (TTM)
—
P/S Ratio (TTM)
1.11
Financial Highlights
Profit Margin
-250.4%
Return on Assets
-543.7%
Return on Equity
1761.9%
Revenue (TTM)
$4.71M
Net Income (TTM)
$-11.79M
Diluted EPS (TTM)
-$3.34
Total Cash (MRQ)
$745,482
Levered FCF (TTM)
$-9.72M
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Earnings Calendar
Next Earnings
Estimated Q3 Release
Nov 12
Est. EPS
Adjusted consensus estimate
$0.04