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Alnylam Pharmaceuticals Inc

ALNY

NASDAQ

Biotechnology

$228.65

USD

+1.53 (+0.67%)

At close: Aug 14, 2026, 4:00 PM EDT

Market Cap $30.39B

Volume 1.5M

Price (USD)
Price (USD)

About Alnylam Pharmaceuticals Inc

Alnylam Pharmaceuticals, Inc. is a biopharmaceutical company, which engages in the business of developing and commercializing novel therapeutics based on ribonucleic acid interference. The company is headquartered in Cambridge, Massachusetts and currently employs 2,500 full-time employees. The company went IPO on 2004-05-28. The firm is engaged in discovering, developing, manufacturing and commercializing novel therapeutics based on ribonucleic acid interference (RNAi). Its marketed products include AMVUTTRA (vutrisiran) for the treatment of hereditary transthyretin-mediated amyloidosis (hATTR) with polyneuropathy in adults; ONPATTRO (patisiran) for the treatment of the polyneuropathy of hATTR amyloidosis in adults; GIVLAARI (givosiran) for the treatment of adults with acute hepatic porphyria; OXLUMO (lumasiran) for the treatment of primary hyperoxaluria type 1, and Leqvio (inclisiran), which is being developed and commercialized by its partner, Novartis AG, for the treatment of adults with hypercholesterolemia or mixed dyslipidemia. The Company’s clinical development programs include Cemdisiran, Fitusiran, Zilebesiran, Elebsiran, Mivelsiran and ALN-HTT02. The company is developing Cemdisiran to treat complement-mediated diseases.

CEO

Dr. Yvonne Greenstreet

HQ

Cambridge, MASSACHUSETTS, US

Founded

2004

Employees

2,500

Quantli Score

8.4

Outperform

Fin. Health

8.1

Profitability

7.6

Growth

9.0

Cash-Flow Q.

8.8

Key Metrics

6 metrics our research team weighs before forming a view on ALNY.

Based on Quantli research · SEC filings · as of Q2 2026

METRIC

VALUE

CHANGE

TREND (3Y)

Revenue Growth (TTM)

95.1%

+90.1 pp

Gross Margin (TTM)

79.8%

-4.1 pp

Operating Margin (TTM)

20.8%

+28.1 pp

Net Margin (TTM)

16.8%

+28.4 pp

ROE (TTM)

59.7%

+173.7 pp

Free Cash Flow (TTM)

$793.95M

Financial Snapshot

Full Financials

Revenue

$4.80B

+95.1%

YoY

Gross Margin

80%

TTM

-4.9%

YoY

Net Income

$807.99M

+382.7%

YoY

Operating Cash Flow

$885.89M

+2236.7%

YoY

Key Statistics

Open

$223.52

Previous Close

$227.12

Day Range

$220.23 - $228.98

52 Week Range

$197.81 - $495.55

Volume

1.5M

Average Volume (10 Days)

2.4M

Dividend Yield

Valuation Measurement

Market Cap

$30.39B

P/E Ratio (TTM)

37.61

P/S Ratio (TTM)

6.33

Price / Book

22.44

Financial Highlights

Profit Margin

16.8%

Return on Assets

14.5%

Return on Equity

59.7%

Revenue (TTM)

$4.80B

Net Income (TTM)

$807.99M

Diluted EPS (TTM)

$5.88

Total Cash (MRQ)

$1.71B

Levered FCF (TTM)

$793.95M

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Best for:

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Position Strategy

Ride market cycles. Patient hold.

Best for:

Patient investors

Swing Strategy

Buy support, sell on recovery.

Best for:

Risk-tolerant

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Earnings Calendar

Next Earnings

Estimated Q3 Release

Oct 28

Est. EPS

Adjusted consensus estimate

$1.68

Analyst Consensus

Buy

Based on 4 analyst ratings

Avg Target: $431.25

(+88.6% upside)

High: $470.00 · Low: $380.00

Strong Buy

0%

Buy

100%

Hold

0%

Sell

0%

Strong Sell

0%

View full analyst ratings