Alnylam Pharmaceuticals Inc
ALNY
NASDAQ
Biotechnology
$228.65
USD
+1.53 (+0.67%)
At close: Aug 14, 2026, 4:00 PM EDT
Market Cap $30.39B
Volume 1.5M
About Alnylam Pharmaceuticals Inc
Alnylam Pharmaceuticals, Inc. is a biopharmaceutical company, which engages in the business of developing and commercializing novel therapeutics based on ribonucleic acid interference. The company is headquartered in Cambridge, Massachusetts and currently employs 2,500 full-time employees. The company went IPO on 2004-05-28. The firm is engaged in discovering, developing, manufacturing and commercializing novel therapeutics based on ribonucleic acid interference (RNAi). Its marketed products include AMVUTTRA (vutrisiran) for the treatment of hereditary transthyretin-mediated amyloidosis (hATTR) with polyneuropathy in adults; ONPATTRO (patisiran) for the treatment of the polyneuropathy of hATTR amyloidosis in adults; GIVLAARI (givosiran) for the treatment of adults with acute hepatic porphyria; OXLUMO (lumasiran) for the treatment of primary hyperoxaluria type 1, and Leqvio (inclisiran), which is being developed and commercialized by its partner, Novartis AG, for the treatment of adults with hypercholesterolemia or mixed dyslipidemia. The Company’s clinical development programs include Cemdisiran, Fitusiran, Zilebesiran, Elebsiran, Mivelsiran and ALN-HTT02. The company is developing Cemdisiran to treat complement-mediated diseases.
CEO
Dr. Yvonne Greenstreet
HQ
Cambridge, MASSACHUSETTS, US
Founded
2004
Employees
2,500
Quantli Score
8.4
Outperform
Fin. Health
8.1
Profitability
7.6
Growth
9.0
Cash-Flow Q.
8.8
Key Metrics
6 metrics our research team weighs before forming a view on ALNY.
Based on Quantli research · SEC filings · as of Q2 2026
METRIC
VALUE
CHANGE
TREND (3Y)
Revenue Growth (TTM)
95.1%
+90.1 pp
Gross Margin (TTM)
79.8%
-4.1 pp
Operating Margin (TTM)
20.8%
+28.1 pp
Net Margin (TTM)
16.8%
+28.4 pp
ROE (TTM)
59.7%
+173.7 pp
Free Cash Flow (TTM)
$793.95M
—
Financial Snapshot
Revenue
$4.80B
+95.1%
YoY
Gross Margin
80%
TTM
-4.9%
YoY
Net Income
$807.99M
+382.7%
YoY
Operating Cash Flow
$885.89M
+2236.7%
YoY
Key Statistics
Open
$223.52
Previous Close
$227.12
Day Range
$220.23 - $228.98
52 Week Range
$197.81 - $495.55
Volume
1.5M
Average Volume (10 Days)
2.4M
Dividend Yield
—
Valuation Measurement
Market Cap
$30.39B
P/E Ratio (TTM)
37.61
P/S Ratio (TTM)
6.33
Price / Book
22.44
Financial Highlights
Profit Margin
16.8%
Return on Assets
14.5%
Return on Equity
59.7%
Revenue (TTM)
$4.80B
Net Income (TTM)
$807.99M
Diluted EPS (TTM)
$5.88
Total Cash (MRQ)
$1.71B
Levered FCF (TTM)
$793.95M
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Earnings Calendar
Next Earnings
Estimated Q3 Release
Oct 28
Est. EPS
Adjusted consensus estimate
$1.68
Analyst Consensus
Based on 4 analyst ratings
Avg Target: $431.25
(+88.6% upside)
High: $470.00 · Low: $380.00
Strong Buy
0%
Buy
100%
Hold
0%
Sell
0%
Strong Sell
0%